Yes, tretinoin can be used during breastfeeding, but there are important precautions to consider. It's not extensively studied during breastfeeding, but the existing evidence suggests it's likely low risk for nursing infants, mainly because it's poorly absorbed after topical application.
However, this isn't a green light to use it without caution. You should avoid oral use while breastfeeding 1 , and wait a week after the last dose before resuming nursing. For topical use, ensure it's not applied directly to the nipple and areola, and be certain that your infant's skin doesn't come into contact with treated areas of your skin.
So while tretinoin usage is possible while breastfeeding, it should only be topical use with careful consideration and adherence to these guidelines. It's always a good idea to consult with your healthcare provider for personalized advice.