Can Evening Primrose Oil Induce Labor?

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By Lucy Chapin | Updated on Jun 24, 2024
Image for article Can Evening Primrose Oil Induce Labor?

Evening Primrose Oil (EPO), whether taken orally or applied vaginally, is thought to produce prostaglandins1 , which help soften or “ripen” the cervix for labor. While some small studies suggest that high doses of vaginal EPO might shorten2  the duration of the early stage of labor and help with cervical ripening specifically for someone having their first baby, there are no large studies to support that EPO decreases the length of active labor, or that EPO will induce labor. 

While it’s likely not harmful to use oral or vaginal EPO, it can be a messy process, and you need to use more than one dose for it to be effective. Essentially, the research is just not strong enough to recommend EPO for cervical ripening or to induce labor.

Pregnant woman holding her stomach on a bed with a plant in the background

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  1. Cleveland Clinic"Prostaglandins"Apr 11, 2022https://my.clevelandclinic.org/health/articles/24411-prostaglandins.

  2. Motahareh Najafi, Marzeyeh Loripoor, Zahra Saghafi, and Majid Kazemi "The effect of vaginal evening primrose on the Bishop score of term nulliparous women"Nursing Practice Today, vol. 6, no. 4Nov 18, 2019, pp. 202-211https://npt.tums.ac.ir/index.php/npt/article/view/539.


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Lucy Chapin
Updated on Jun 24, 2024

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Can Evening Primrose Oil Induce Labor?

 Lucy Chapin Profile Photo
By Lucy Chapin | Updated on Jun 24, 2024
Image for article Can Evening Primrose Oil Induce Labor?

Evening Primrose Oil (EPO), whether taken orally or applied vaginally, is thought to produce prostaglandins1 , which help soften or “ripen” the cervix for labor. While some small studies suggest that high doses of vaginal EPO might shorten2  the duration of the early stage of labor and help with cervical ripening specifically for someone having their first baby, there are no large studies to support that EPO decreases the length of active labor, or that EPO will induce labor. 

While it’s likely not harmful to use oral or vaginal EPO, it can be a messy process, and you need to use more than one dose for it to be effective. Essentially, the research is just not strong enough to recommend EPO for cervical ripening or to induce labor.

Pregnant woman holding her stomach on a bed with a plant in the background

Want evidence-based health & wellness advice for fertility, pregnancy, and postpartum delivered to your inbox?

Your privacy is important to us. By subscribing you agree to our Privacy Policy and Terms & Conditions.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Expectful uses only high-quality sources, including academic research institutions, medical associations, and subject matter experts.

  1. Cleveland Clinic"Prostaglandins"Apr 11, 2022https://my.clevelandclinic.org/health/articles/24411-prostaglandins.

  2. Motahareh Najafi, Marzeyeh Loripoor, Zahra Saghafi, and Majid Kazemi "The effect of vaginal evening primrose on the Bishop score of term nulliparous women"Nursing Practice Today, vol. 6, no. 4Nov 18, 2019, pp. 202-211https://npt.tums.ac.ir/index.php/npt/article/view/539.


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