Yes, you can take Zofran, also known as ondansetron, while breastfeeding.
Zofran is the go-to for tackling nausea, especially during and after a cesarean section. Typical doses range from four to eight micrograms and are usually given intravenously. And good news: it seems like it doesn't really have an impact on the onset of breastfeeding, so there's no need to worry about that.
What about any potential side effects for the baby? So far, none have been reported 1 in either the immediate postpartum setting or among women who took Zofran postpartum as part of a pharmacokinetic study.
However, Zofran's use in breastfeeding mothers beyond the immediate postpartum setting hasn't been thoroughly researched, but it’s labeled for use in infants as young as one month old. A computer model even showed that the amounts in milk are much less than this dose.
The bottom line: taking Zofran while breastfeeding is likely okay, but definitely check in with your healthcare provider to be sure.