Yes, you can take Wellbutrin, also known as bupropion, while breastfeeding, but there are some points to consider.
Studies suggest that maternal doses of up to 300 mg daily result in low levels in breastmilk and shouldn’t cause any adverse effects in breastfed infants. That sounds like good news, but there's a “but”: there have been some reports of potential seizures 1 in partially breastfed six-month-olds, so that's something to be mindful of.
A safety scoring system also recommends caution when using bupropion during breastfeeding. It's not necessarily a no-go for breastfeeding if you need to take bupropion, but another drug might be a better option, especially when nursing a newborn or preterm infant.
And here's another thing: if you're taking an SSRI along with bupropion, keep a close watch on your little one for any changes like vomiting, diarrhea, or unusual sleepiness. If in doubt, get a serum level check to rule out toxicity.
In the end, while it's possible to use Wellbutrin while breastfeeding, it's super important to discuss it with your doctor to ensure it's the best decision for both you and your baby.