Retinol use isn’t recommended during pregnancy.
There are no specific studies that look at the use of topical retinol in pregnancy, but it’s known that oral retinoids, such as isotretinoin 1 (Accutane), are teratogenic and can lead to fetal defects. Since there aren’t enough studies and evidence investigating the use of topical retinoids on your skin in pregnancy, it’s best to avoid the use of all topical or oral retinoids and retinol during this time.
As an alternative, some ingredients that may be safe for use while pregnant include azelaic acid or low concentrations of AHAs like glycolic acid. While some consider bakuchiol, a plant-based retinol alternative, to be safe, there are no studies looking at its use in pregnancy, so it should be avoided.